Peptide Database

Peptide NameHepcidin

Function Ontology

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Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC86H146N24O26S9

DescriptionStandard

        ICMFCCDCCQKSKCGLCCKT
    

Molecular Weight2220.81 Da

Isoelectric Point (pI)8.21

Net Charge (pH 7.0)1.68

Net Charge (pH 7.4) 1.35

Charge Density (pH 7.0) 0.0839

GRAVY Index0.62

Hydrophobic Moment 0.30

Boman Index0.03

Instability Index31.66

Aliphatic Index 39.00

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 815.13

LogP -9.73

H-bond Donors 36.0

H-bond Acceptors 37.0

Rotatable Bonds 75.0

Heavy Atoms 145.0

Ring Count 1.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0265336 VERIFIED: YES

Provenance & Taxonomy

OrganismOrycteropus afer [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)