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MYP_166400
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Basic Information
AMPR-11
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C95H156N26O27S4
Standard
Sequence
KTMMQSGGTFGTFMAIGMGIR
Physicochemical Analysis
2222.67 Da
11.00
1.76
1.55
0.0838
0.34
0.37
0.26
36.86
41.90
0.0952
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
857.25
-9.35
31.0
33.0
76.0
152.0
2.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009898 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Carbapenem-resistant Pseudomonas aeruginosa, Carbapenem-resistant Acinetobacter baumannii
50 μM
MBC
PaperRomo1-Derived Antimicrobial Peptide Is a New Antimicrobial Agent against Multidrug-Resistant Bacteria in a Murine Model of Sepsis.
RECORD: Rec_0026666 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Anti-Gram-positive
Vancomycin-resistant Staphylococcus aureus
120 μg/mL
MBC
PMID32291307 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32291307/
RECORD: Rec_0038585 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Anti-Gram-positive Hemolytic
duced a hemolysis of 23%
256 μg/mL
Hemolysis
PMID32291307 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32291307/
RECORD: Rec_0041988 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter baumannii
45 μM
MBC
PaperRomo1-Derived Antimicrobial Peptide Is a New Antimicrobial Agent against Multidrug-Resistant Bacteria in a Murine Model of Sepsis.
RECORD: Rec_0043906 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Anti-Gram-positive
aerogenes
90 μg/mL
MBC
PMID32291307 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32291307/
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