Peptide Database

Peptide NameDifelikefalin

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Kappa-opioid agonist

Standard Statusnot Standard

Sequence Length5 amino acids

Chemical Formula-

Descriptioncontains X representing unresolved or non-standard residue

        FFLKX
    

Molecular Weight0.00 Da

Isoelectric Point (pI)0.00

Net Charge (pH 7.0)0.00

GRAVY Index0.00

Boman Index0.00

Instability Index0.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0319004 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyKappa-opioid peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

C-Termγ-(4-N-piperidinyl)amino carboxylic acid

Other ModsNon-standard residues/X at 5

Bio-Activity Profile

Function

Analgesic Antipruritic Kappa-opioid agonist

Targetκ-opioid receptor

Half-LifeClinical/Human: 23-31 h