Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC743H1170N216O218S8

DescriptionStandard

        MAKVQFKPRSETTLLIVHCSATKPTMNIGLREIRQWHKEKGWLDVGYHFIIRRDGTVEDGREVSAIGAHCEGKNYTSVGVCLVGGVNEKMQPEANFTPQQMESLKTLLAGLKREYPQASIHGHHDFAAKACPSFDVQRWLKSGELVTSDHG
    

Molecular Weight16873.07 Da

Isoelectric Point (pI)8.37

Net Charge (pH 7.0)2.18

Net Charge (pH 7.4) 1.46

Charge Density (pH 7.0) 0.0144

GRAVY Index-0.46

Hydrophobic Moment 0.75

Boman Index-0.03

Instability Index42.25

Aliphatic Index 74.24

Aromaticity 0.0728

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6966.73

LogP -70.47

H-bond Donors 245.0

H-bond Acceptors 236.0

Rotatable Bonds 564.0

Heavy Atoms 1185.0

Ring Count 28.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0045118 VERIFIED: NO

Provenance & Taxonomy

OrganismErwinia phage pEp_SNUABM_12 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic