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MYP_166291
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Basic Information
Indolicidin [W9L]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C95H132N24O14
Standard
Sequence
ILPWKWPWLPWRR
Physicochemical Analysis
1834.22 Da
12.00
2.76
2.55
0.2122
-0.71
0.43
0.04
100.58
90.00
0.3077
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
599.13
3.42
22.0
17.0
48.0
133.0
11.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000528 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli IFO 12734
12.5 μg/mL
MIC
PMID20196123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20196123/
RECORD: Rec_0034545 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 9017656 B2 Evidence URLhttps://patents.google.com/patent/US9017656B2/en PatentUS 9017656 B2
RECORD: Rec_0080919 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
50 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/20196123/ PMID20196123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20196123/
RECORD: Rec_0119563 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis IFO 3513
1.56 μg/mL
MIC
PMID20196123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20196123/
RECORD: Rec_0124209 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Indolicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Gram- Escherichia coli IFO 12734
12.5 μg/mL
MIC
PaperStructure-function relationships in the tryptophan-rich, antimicrobial peptide indolicidin. PMID11695650 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11695650/
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