Peptide Database

Peptide NameDefensin alpha 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC444H719N131O143S7

DescriptionStandard

        MRTLAILAAILLVALQAQAESLQERADEVATQEQPGEDDQDLAVSFEENGLSTLRASGSQARRTCYCRTGRCYTPEFHSGKCLFKGLTYKLCCR
    

Molecular Weight10404.71 Da

Isoelectric Point (pI)5.77

Net Charge (pH 7.0)-1.45

Net Charge (pH 7.4) -1.83

Charge Density (pH 7.0) -0.0154

GRAVY Index-0.30

Hydrophobic Moment 0.56

Boman Index-0.08

Instability Index41.80

Aliphatic Index 79.04

Aromaticity 0.0638

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4469.98

LogP -51.35

H-bond Donors 163.0

H-bond Acceptors 150.0

Rotatable Bonds 351.0

Heavy Atoms 725.0

Ring Count 9.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0254149 VERIFIED: YES

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyDefensin

Tax ID9555

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Non-hemolytic Non-ribosomal

RECORD: Rec_0264948 VERIFIED: NO