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MYP_166240
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Basic Information
Polymyxin E7
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XTXXXLLXXT
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0034006 VERIFIED: YES
Provenance & Taxonomy
Paenibacillus spp.,Paenibacillus polymyxa [Bacterium]
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 1,3,4,5,8,9
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii
16-128 μg/mL
MIC
PMID24601489;31645764 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24601489/
RECORD: Rec_0046608 VERIFIED: YES
Provenance & Taxonomy
Paenibacillus spp.,Paenibacillus polymyxa [Bacterium]
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 1,3,4,5,8,9
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecium ATCC 70022
32 μg/mL
MIC
PMID24601489;31645764 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24601489/
RECORD: Rec_0050667 VERIFIED: YES
Provenance & Taxonomy
Paenibacillus spp.,Paenibacillus polymyxa [Bacterium]
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 1,3,4,5,8,9
Bio-Activity Profile
Antimicrobial Antibacterial
Neisseria gonorrhoeae 49226
128 μg/mL
MIC
PMID24601489;31645764 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24601489/
RECORD: Rec_0088263 VERIFIED: YES
Provenance & Taxonomy
Paenibacillus spp.,Paenibacillus polymyxa [Bacterium]
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 1,3,4,5,8,9
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
2 μg/mL
MIC
PMID24601489;31645764 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24601489/
RECORD: Rec_0089251 VERIFIED: YES
Provenance & Taxonomy
Paenibacillus spp.,Paenibacillus polymyxa [Bacterium]
Structure & Mods
linear peptide [Linear]
D-residue-containing modified peptide [Mixed]
unspecified non-canonical residue at 1,3,4,5,8,9
Bio-Activity Profile
Hemolytic
Vero cells
87±7 μg/mL
Cytotoxicity
PMID24601489;31645764 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24601489/
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