Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC547H879N151O165S2

DescriptionStandard

        PDLSGHEKFGLGNVKYNISRIHVTDIELPSAFISLLRGSGIKLVIGNASLTIDMNWNIRTWIFKDSGRGTVHVSKAFVTAIFSTPLDNAGPTSISLTSCRTTSGDVDIKLNGKT
    

Molecular Weight12274.87 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)3.22

Net Charge (pH 7.4) 2.97

Charge Density (pH 7.0) 0.0282

GRAVY Index0.01

Hydrophobic Moment 0.55

Boman Index0.10

Instability Index18.17

Aliphatic Index 97.46

Aromaticity 0.0702

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5063.60

LogP -56.55

H-bond Donors 181.0

H-bond Acceptors 173.0

Rotatable Bonds 407.0

Heavy Atoms 865.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0149748 VERIFIED: NO

Provenance & Taxonomy

OrganismPeucedramus taeniatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria