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MYP_166189
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Basic Information
Saha-CATH5 (cathelicidins; mammals, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C104H197N37O21
Standard
Sequence
KRIGLIRLIGKILRGLRRLG
Physicochemical Analysis
2301.91 Da
12.00
6.76
6.55
0.3379
0.26
0.98
-0.15
70.59
175.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
977.76
-5.88
38.0
28.0
85.0
162.0
0.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184064 VERIFIED: YES
Provenance & Taxonomy
Sarcophilus harrisii [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
C. parapsilosis ATCC 22019
64 μg/mL
MIC
PMID27725697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27725697/
RECORD: Rec_0194436 VERIFIED: YES
Provenance & Taxonomy
Tasmanian devil,Sarcophilus harrisii [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
faecalis
PMID27725697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27725697/
RECORD: Rec_0194447 VERIFIED: YES
Provenance & Taxonomy
Tasmanian devil,Sarcophilus harrisii [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
pyogenes ATCC 19615
PMID27725697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27725697/
RECORD: Rec_0196929 VERIFIED: YES
Provenance & Taxonomy
Sarcophilus harrisii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A549 (Not active up to 500 μg/ml)
PaperPubMed PMID: 27725697 PMID27725697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27725697/
RECORD: Rec_0198408 VERIFIED: YES
Provenance & Taxonomy
Sarcophilus harrisii [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis
64 μg/mL
MIC
PMID27725697 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27725697/
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