MYP_166173
Basic Information
5
Antiviral
Standard
35 amino acids
C187H277N47O64
Standard
Sequence
IEEQAKTFLDKFNHEKEDLEYQSSLASWNYNTNIT
Physicochemical Analysis
4207.48 Da
4.49
-4.14
-4.41
-0.1183
-1.11
0.53
-0.14
71.11
61.43
0.1429
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1856.73
-18.96
62.0
61.0
142.0
298.0
7.0
40.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0090403 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Stapled ACE2-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus 2
3.6 μM
IC50
RECORD: Rec_0141827 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
ACE2-derived
32630
Structure & Mods
lactam-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Ⓚ (16) and Ⓔ (20) are corss-linked by lactam stapling
Bio-Activity Profile
Antiviral
SARS-CoV-2 spike protein-hACE2 complex
3.6 μM
IC50
RECORD: Rec_0195578 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Stapled ACE2-derived peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus 2
100 μM
IC50