‹ ›
MYP_166158
← PREVIOUS NEXT → BACK
Basic Information
[Lys6] TG
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
11 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XGLXGKLXGIX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0374287 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
None
X(1)=TOAC; X(4/8)=Aib; X(11)=Lol (Amino alcohol leucinol)
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PaperThe rational search for selective anticancer derivatives of the peptide Trichogin GA IV: a multi-technique biophysical approach. Sci Rep. 2016 Apr 4;6:24000. doi: 10.1038/srep24000. PMID: 27039838. PMID27039838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27039838/
RECORD: Rec_0376058 VERIFIED: YES
Provenance & Taxonomy
Ascomycetes [Fungus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
None
X(1/4/8)=Aib; X(11)=Lol (Amino alcohol leucinol)
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HeLa
2 μM
EC50
PMID25306964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25306964/
RECORD: Rec_0385171 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
None
X(1/4/8)=Aib; X(11)=Lol (Amino alcohol leucinol)
Bio-Activity Profile
Antimicrobial Anticancer
HeLa
3 μM
EC50
PaperThe rational search for selective anticancer derivatives of the peptide Trichogin GA IV: a multi-technique biophysical approach. Sci Rep. 2016 Apr 4;6:24000. doi: 10.1038/srep24000. PMID: 27039838. PMID27039838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27039838/
RECORD: Rec_0398467 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
None
X(1)=TOAC; X(4/8)=Aib; X(11)=Lol (Amino alcohol leucinol)
Bio-Activity Profile
Antimicrobial Anticancer
T67
4 μM
EC50
PaperThe rational search for selective anticancer derivatives of the peptide Trichogin GA IV: a multi-technique biophysical approach. Sci Rep. 2016 Apr 4;6:24000. doi: 10.1038/srep24000. PMID: 27039838. PMID27039838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27039838/
RECORD: Rec_0403228 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Oct (Fatty acid 1-Octanoyl)
None
X(1/4/8)=Aib; X(11)=Lol (Amino alcohol leucinol)
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HeLa
2 μM
EC50
PaperThe rational search for selective anticancer derivatives of the peptide Trichogin GA IV: a multi-technique biophysical approach. Sci Rep. 2016 Apr 4;6:24000. doi: 10.1038/srep24000. PMID: 27039838. PMID27039838 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27039838/
FIRST PREV 1 2 3 4 5 NEXT LAST
Showing 5 records on this page · Page 4 of 5