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MYP_166113
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Basic Information
Stomoxyn (Insects, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
42 amino acids
C197H329N61O54
Standard
Sequence
RGFRKHFNKLVKKVKHTISETAHVAKDTAVIAGSGAAVVAAT
Physicochemical Analysis
4416.10 Da
10.66
6.02
5.65
0.1433
-0.00
0.78
0.02
0.66
88.33
0.0476
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1861.45
-20.19
67.0
63.0
150.0
312.0
5.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0334697 VERIFIED: YES
Provenance & Taxonomy
Stomoxys calcitrans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus pyogenes
1.56-3.12 μM
MIC
PMID12372834;16170803 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12372834/
RECORD: Rec_0339248 VERIFIED: YES
Provenance & Taxonomy
Stomoxys calcitrans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0342042 VERIFIED: YES
Provenance & Taxonomy
Stomoxys calcitrans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID12372834;16170803 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12372834/
RECORD: Rec_0344015 VERIFIED: YES
Provenance & Taxonomy
Stomoxys calcitrans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli K12 RM148
0.19-0.39 μM
MIC
PMID12372834;16170803 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12372834/
RECORD: Rec_0345492 VERIFIED: YES
Provenance & Taxonomy
Stomoxys calcitrans [Animal]
Stomoxyn
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterobacter cloacae b12
3.12-6.25 μM
MIC
PMID12372834 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12372834/
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