Peptide Database

Peptide Name[P Psi C]BN(6-14) [Bombesin antagonist]

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Growth inhibitors

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC50H69N13O11S

DescriptionStandard

        FQWAVGHLC
    

Molecular Weight1060.23 Da

Isoelectric Point (pI)6.73

Net Charge (pH 7.0)-0.16

Net Charge (pH 7.4) -0.43

Charge Density (pH 7.0) -0.0181

GRAVY Index0.79

Hydrophobic Moment 0.29

Boman Index0.48

Instability Index-17.24

Aliphatic Index 86.67

Aromaticity 0.2222

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 383.68

LogP -1.24

H-bond Donors 14.0

H-bond Acceptors 13.0

Rotatable Bonds 30.0

Heavy Atoms 75.0

Ring Count 4.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0305024 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyBombesin

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermAmidation

Other ModsCpa=Chlorophenylalanine

Bio-Activity Profile

Function

Growth inhibitors

Activity0.01 μM

MethodIC50

Half-LifeSCLC cell line NCI-H345, in vitro; 9240 s