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MYP_166076
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Basic Information
Formaecin-2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
16 amino acids
C81H131N25O22
Standard
Sequence
GRPNPVNTKPTPYPRL
Physicochemical Analysis
1807.06 Da
11.00
2.76
2.55
0.1724
-1.44
0.33
-0.30
24.63
42.50
0.0625
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
752.56
-8.35
24.0
25.0
49.0
128.0
6.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0203751 VERIFIED: YES
Provenance & Taxonomy
Myrmecia gulosa [Animal]
Formaecin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
PaperJ. Biol. Chem. 273:6139-6143(1998) | http://www.jbc.org/content/273/11/6139.full
RECORD: Rec_0209448 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 37.5%, C 62.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0246891 VERIFIED: YES
Provenance & Taxonomy
Myrmecia gulosa [Animal]
Formaecin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli NCTC 8196
PMID9497332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9497332/
RECORD: Rec_0282918 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0362473 VERIFIED: YES
Provenance & Taxonomy
Red bulldog ant [Animal]
PrAMP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli NCTC 8196
PaperIsolation from an ant Myrmecia gulosa of two inducible O-glycosylated proline-rich antibacterial peptides.
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