Peptide Database

Peptide NameTripartite motif-containing protein 5

Function Ontology

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length497 amino acids

Chemical FormulaC2539H3967N689O758S32

DescriptionStandard

        MASGILLNVKEEVTCPICLELLTEPLSLHCGHSFCQACITANHKKSMLYKEGERSCPVCRISYQPENIQPNRHVANIVEKLREVKLSPEEGQKVDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLMEEVAQEYHVKLQTALEMLRQKQQEAEKLEADIREEKASWKIQIDYDKTNVSADFEQLREILDWEESNELQNLEKEEEDILKSLTKSETEMVQQTQYMRELISELEHRLQGSMMDLLQGVDGIIKRIENMTLKKPKTFHKNQRRVFRAPDLKGMLDMFRELTDARRYWVDVTLAPNNISHAVIAEDKRQVSSRNPQIMYQAPGTLFTFPSLTNFNYCTGVLGSQSITSGKHYWEVDVSKKSAWILGVCAGFQSDAMYNIEQNENYQPKYGYWVIGLQEGVKYSVFQDGSSHTPFAPFIVPLSVIICPDRVGVFVDYEACTVSFFNITNHGFLIYKFSQCSFSKPVFPYLNPRKCTVPMTLCSPSS
    

Molecular Weight57297.90 Da

Isoelectric Point (pI)5.94

Net Charge (pH 7.0)-9.18

Net Charge (pH 7.4) -10.64

Charge Density (pH 7.0) -0.0185

GRAVY Index-0.42

Hydrophobic Moment 0.80

Boman Index-0.04

Instability Index55.14

Aliphatic Index 80.18

Aromaticity 0.0905

Extinction Coeff. Reduced 63830.00

Extinction Coeff. Oxidized 64955.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0254424 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyTRIM

Tax ID9544

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

Bio-Activity Profile

Function

Antiviral Replication inhibitor Interferon pathway modulator Anti-HIV-1

TargetHuman immunodeficiency virus type 1(HIV-1)