Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC346H550N92O90S8

DescriptionStandard

        MRTFLFLFVVLFLLAPARNAFFDEKCFKLNGRCVNSCRKNEELVALCQKSLKCCLTLQPCWKSKDD
    

Molecular Weight7695.15 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.10

Charge Density (pH 7.0) 0.0673

GRAVY Index0.14

Hydrophobic Moment 0.59

Boman Index-0.00

Instability Index33.84

Aliphatic Index 88.64

Aromaticity 0.1212

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2966.26

LogP -22.80

H-bond Donors 109.0

H-bond Acceptors 103.0

Rotatable Bonds 259.0

Heavy Atoms 536.0

Ring Count 11.0

Amide Bonds 71.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0131555 VERIFIED: NO

Provenance & Taxonomy

OrganismOdobenus rosmarus divergens [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0346125 VERIFIED: NO