Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC366H584N104O86S7

DescriptionStandard

        MKLLLLTLTVLLLLSQLTPGGTQRCWNLHGKYRHRCSKKERVYVYCINSKMCCVKPRYQPKGRWWPF
    

Molecular Weight8041.65 Da

Isoelectric Point (pI)10.12

Net Charge (pH 7.0)11.62

Net Charge (pH 7.4) 11.21

Charge Density (pH 7.0) 0.1734

GRAVY Index-0.31

Hydrophobic Moment 0.42

Boman Index-0.07

Instability Index24.53

Aliphatic Index 87.16

Aromaticity 0.1194

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22710.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3082.31

LogP -21.19

H-bond Donors 116.0

H-bond Acceptors 107.0

Rotatable Bonds 263.0

Heavy Atoms 563.0

Ring Count 17.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0202917 VERIFIED: NO

Provenance & Taxonomy

OrganismAotus nancymaae [Animal]

FamilyDefensin

Tax ID37293

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence