Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC381H602N112O108S10

DescriptionStandard

        MKTFLFLFAVLFFWSQPRMHFFEKCSRINGRCTASCLKNEELVALCQKNLKCCVTVQSCGRSKGNQSDEGSGHMGTRG
    

Molecular Weight8800.19 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)5.61

Net Charge (pH 7.4) 5.18

Charge Density (pH 7.0) 0.0719

GRAVY Index-0.20

Hydrophobic Moment 0.62

Boman Index-0.04

Instability Index47.55

Aliphatic Index 58.72

Aromaticity 0.1026

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3587.75

LogP -40.11

H-bond Donors 133.0

H-bond Acceptors 126.0

Rotatable Bonds 299.0

Heavy Atoms 611.0

Ring Count 12.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0334087 VERIFIED: NO

Provenance & Taxonomy

OrganismMus spicilegus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence