Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length454 amino acids

Chemical FormulaC2265H3574N572O651S16

DescriptionStandard

        MFLWCVLVLLNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTEKVDPIGKVQYSFTGMQIVNLGLPKSALVLVPDTGVMLSIGNAYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTVAVMSDDTGRPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALRNALQKQICPLVADSIADINPHLKTLNVLAKVDQYAEIEYSMVGSPVISNTSIDLGLKGEFYNIGQHKEPPFSPTPFSLPSQDTDMLYIGVSAFTINSAGFVYNRAGALHLYITDDMIPSGSPIRLNTKTFGAFIPQIEKMYPGLMMKLLVETVKEPIVTFEPNNMTVQASSTVTAYAIQPNSTLSPLFVLNLEGSVSTHIYVTELKLAGNVTLNNEKLQVHFYWFFFFSFSARLQEGYPLPAIGKMQLVNSQLKVLKDYLLIGTDVQFTG
    

Molecular Weight49747.09 Da

Isoelectric Point (pI)8.51

Net Charge (pH 7.0)3.10

Net Charge (pH 7.4) 2.39

Charge Density (pH 7.0) 0.0068

GRAVY Index0.19

Hydrophobic Moment 0.72

Boman Index0.18

Instability Index29.31

Aliphatic Index 102.58

Aromaticity 0.0947

Extinction Coeff. Reduced 47330.00

Extinction Coeff. Oxidized 47455.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0017180 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria