Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length484 amino acids

Chemical FormulaC2393H3848N596O675S17

DescriptionStandard

        VLFSVLWDLTTVKMSPCCWLALVALIPVTLGTNPGVEVRLTQTGLDYGRQLGIAAIQQKLKSIKIPDISGTQHVSPIGKVQYTFMQIVKVGLPQSAVGLVPGTGITLSINNAFISLHGNWRVKYLKIIKDSGSFDLNVNGLTISITIAIKSDGTGRPAVSAVSCGASIASVSIKFHGGASWLYNLFTKFIEKALRSALQKQICPLVVDAVSDLNPYLKTLNVEAQVDKYAEIEYSMVSSPTVSKSSIDLSLKGEFYSIGKHQEPPFSPIAFSLPPQVNNMLYMGMSAFTANSAAFVYDKAGALSLYVTDDMIPQSSPLRLNTKTFGAFIPQLTKLFPGLMMKLLVKTVKTPIVTFKPNNVTIQATGTVTAYAIQPNATLSPLFVLNLETSVSAQLFVSEMRLAGAVTLNKMSFTLGTSYVGQFQVGTLDNILQIVLKVVVIPKLNVQLAKGYPLPSIGKMKLVKTQLQVLKDYMLIGTDVQFTS
    

Molecular Weight52312.84 Da

Isoelectric Point (pI)9.51

Net Charge (pH 7.0)16.04

Net Charge (pH 7.4) 15.47

Charge Density (pH 7.0) 0.0331

GRAVY Index0.34

Hydrophobic Moment 0.83

Boman Index0.21

Instability Index31.70

Aliphatic Index 109.11

Aromaticity 0.0826

Extinction Coeff. Reduced 44350.00

Extinction Coeff. Oxidized 44600.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0064795 VERIFIED: NO

Provenance & Taxonomy

OrganismAnabas testudineus (Climbing perch) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria