Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length448 amino acids

Chemical FormulaC2258H3556N596O637S13

DescriptionStandard

        TNPGFVVRITQAGLDYAQEQGIAILEKELAQLKLPDISGDSRVLRVGKVHYELSRLRLRDFQLPYSRITPISNVGLQVSISNAFAELDGDWRVKFLFIRDHGSFDLKVENIYIKILLRLGSDTTGRPTISTPDCSAHISKVRVLFSGKLAWLYNLFHRVIESRLRKILEDKVCDNVAKSVHNELQTYMRTLPVTAKIDNKFGIAYSLVAPPRATAQSLDADLKGEFYSLAHRSPVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHEAGALVFEITEAMIPKDVEFKLDTSVFSAFIPQLEEMYPNMPMKFRLSAPTAPFLTIGPGGISFQPIVDAQAYAILPNSSLAPLFLLSLVSSDTACGDGAEGSLSSPLLSLCRIRLSLKDSAVGTFQVRMMQSLMNILTSNVLLPHLNVQLPGPVAAQRFLSFSQNFLLLGADVRFQPR
    

Molecular Weight49660.84 Da

Isoelectric Point (pI)8.53

Net Charge (pH 7.0)3.19

Net Charge (pH 7.4) 2.39

Charge Density (pH 7.0) 0.0071

GRAVY Index0.10

Hydrophobic Moment 0.69

Boman Index0.11

Instability Index40.62

Aliphatic Index 101.45

Aromaticity 0.0960

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0276069 VERIFIED: NO

Provenance & Taxonomy

OrganismMolothrus ater [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria