Peptide Database

Peptide NameCorazonin precursor-related peptide

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC164H248N44O56

DescriptionStandard

        SFNAASPLLTTGHLHRGSELGLSDLYDLQEWTSD
    

Molecular Weight3731.98 Da

Isoelectric Point (pI)4.56

Net Charge (pH 7.0)-4.35

Net Charge (pH 7.4) -4.67

Charge Density (pH 7.0) -0.1281

GRAVY Index-0.40

Hydrophobic Moment 0.41

Boman Index0.07

Instability Index36.68

Aliphatic Index 86.18

Aromaticity 0.0882

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1604.63

LogP -18.33

H-bond Donors 56.0

H-bond Acceptors 54.0

Rotatable Bonds 119.0

Heavy Atoms 264.0

Ring Count 7.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0230629 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila erecta [Animal]

FamilyCorazonin

Tax ID7220

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone

RECORD: Rec_0271085 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0424540 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila erecta [Animal]

FamilyCorazonin precursor-related peptide

Tax ID7220

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation ACE inhibitory

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour