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MYP_165962
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
11 amino acids
C57H102N24O13S2
Standard
Sequence
RCFRRRGKLTC
Physicochemical Analysis
1395.70 Da
11.54
4.74
4.51
0.4308
-1.04
0.58
-0.76
90.08
35.45
0.0909
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
648.17
-7.41
28.0
20.0
48.0
96.0
1.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018284 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Murine macrophage cells RAW 264.7[70-80% Killing = 256 microg/ml
PMID30610885 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30610885/
RECORD: Rec_0039453 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0063116 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Murine macrophage cells RAW 264.7[10-20% Killing = 32-64 microg/ml
PMID30610885 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30610885/
RECORD: Rec_0082024 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
PMID30610885 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30610885/
RECORD: Rec_0090663 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
2-11
Bio-Activity Profile
Antimicrobial Anti-inflammatory Immunomodulatory
Escherichia coli ATCC 8739
4 μg/mL
MIC
PaperHost-defense peptides AC12, DK16 and RC11 with immunomodulatory activity isolated from Hypsiboas raniceps skin secretion
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