Peptide Database

Peptide Name[Y19A]GexIVA[1,2]

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC133H227N55O40S4

DescriptionStandard

        TCRSSGRYCRSPYDRRRRACRRITDACV
    

Molecular Weight3364.83 Da

Isoelectric Point (pI)10.69

Net Charge (pH 7.0)6.36

Net Charge (pH 7.4) 6.11

Charge Density (pH 7.0) 0.2271

GRAVY Index-1.20

Hydrophobic Moment 0.86

Boman Index-0.69

Instability Index177.19

Aliphatic Index 31.43

Aromaticity 0.0714

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1613.54

LogP -22.96

H-bond Donors 68.0

H-bond Acceptors 51.0

Rotatable Bonds 110.0

Heavy Atoms 232.0

Ring Count 3.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0146463 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyConotoxin

Tax ID32630

Structure & Mods

Configdisulfide-constrained linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-9; 20-27

Bio-Activity Profile

Function

Analgesic

Targetα9α10 nicotinic acetylcholine receptor

RECORD: Rec_0396992 VERIFIED: YES