Peptide Database

Peptide NameSLAY-screened peptide P3893

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC89H144N30O34

DescriptionStandard

        RVAGPDADSINKLDNHDLNN
    

Molecular Weight2178.28 Da

Isoelectric Point (pI)4.56

Net Charge (pH 7.0)-2.15

Net Charge (pH 7.4) -2.41

Charge Density (pH 7.0) -0.1075

GRAVY Index-1.12

Hydrophobic Moment 0.45

Boman Index-0.25

Instability Index18.71

Aliphatic Index 83.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1065.82

LogP -14.67

H-bond Donors 34.0

H-bond Acceptors 33.0

Rotatable Bonds 72.0

Heavy Atoms 153.0

Ring Count 2.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0408812 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/