Peptide Database

Peptide NameHNH endonuclease domain protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length257 amino acids

Chemical FormulaC1252H2021N399O391S4

DescriptionStandard

        RARAELNQANEDVARNQERQAKAVQVYNSRKSELDAANKTLADAIAEIKQFDRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAKEKSDADAALSAAQERRKQKENKEKDAKDKLDKESKRNKPGKATGKGKPVGDKWLDDAGKDSGAPIPDRIADKLRDKEFKNFDDFRKKFWEEVSKDPDLSKQFKGSNKTNIQKGKAPFARKKDQVGGRERFELHHDKPISQDGGVYDMNNIRVTTPKRHIDIHRGK
    

Molecular Weight29047.14 Da

Isoelectric Point (pI)9.73

Net Charge (pH 7.0)15.32

Net Charge (pH 7.4) 14.71

Charge Density (pH 7.0) 0.0596

GRAVY Index-1.31

Hydrophobic Moment 0.73

Boman Index-0.36

Instability Index31.82

Aliphatic Index 51.83

Aromaticity 0.0584

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0296039 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli MS 84-1 [Bacterium]

FamilyPyocin/Colicin

Tax ID749533

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal