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MYP_165923
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Basic Information
P8
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
15 amino acids
C96H156N46O18S
Standard
Sequence
RRWRRWNRFNRRRCR
Physicochemical Analysis
2274.63 Da
12.00
8.75
8.53
0.5833
-2.93
0.80
-1.42
246.68
0.00
0.2000
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1145.58
-12.07
48.0
28.0
76.0
161.0
5.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029782 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus 1199B
25 μM
MIC
PMID26837216 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26837216/
RECORD: Rec_0050831 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
None
Linker 6-aminohexamoic acid (Ahx)
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25459448 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25459448/
RECORD: Rec_0101571 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Ahx, 6-aminohexamoic acid
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID25459448 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25459448/
RECORD: Rec_0135350 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human RBC
50 μM
Hemolysis
PMID26837216 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26837216/
RECORD: Rec_0233590 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Ahx, 6-aminohexamoic acid
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID25459448 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25459448/
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