Peptide Database

Peptide NameNisin A

Function Ontology

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Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC137H234N40O45S6

DescriptionStandard

        ITSISLCTPGCKTGALMGCSAATATCHCSIHVSK
    

Molecular Weight3353.95 Da

Isoelectric Point (pI)8.43

Net Charge (pH 7.0)1.88

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0554

GRAVY Index0.66

Hydrophobic Moment 0.29

Boman Index0.25

Instability Index27.52

Aliphatic Index 77.65

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1326.53

LogP -19.78

H-bond Donors 53.0

H-bond Acceptors 55.0

Rotatable Bonds 107.0

Heavy Atoms 228.0

Ring Count 3.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409699 VERIFIED: YES

Provenance & Taxonomy

OrganismLactococcus lactis [Bacterium]

FamilyBacteriocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)