Peptide Database

Peptide NameParathyroid hormone

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC406H670N122O126S3

DescriptionStandard

        AVSEIQLMHNLGKHLASVERMQWLRKKLQDVHNFVSLGVQMAAREGSYQRPTKKEENVLVDGNSKSLGEGDKADVDVLVKAKSQ
    

Molecular Weight9372.60 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)2.07

Net Charge (pH 7.4) 1.70

Charge Density (pH 7.0) 0.0246

GRAVY Index-0.58

Hydrophobic Moment 0.60

Boman Index-0.13

Instability Index34.24

Aliphatic Index 88.10

Aromaticity 0.0357

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4076.71

LogP -43.66

H-bond Donors 139.0

H-bond Acceptors 134.0

Rotatable Bonds 331.0

Heavy Atoms 657.0

Ring Count 8.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004254 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyParathyroid hormone

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0132427 VERIFIED: YES