Peptide Database

Peptide NameIL-24

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length155 amino acids

Chemical FormulaC828H1286N220O230S5

DescriptionStandard

        QEFHFGPCQVKGVVPQKLWEAFWAVKDTMQAQDNITSARLLQQEVLQNVSDAESCYLVHTLLEFYLKTVFKNYHNRTVEVRTLKSFSTLANNFVLIVSQLQPSQENEMFSIRDSAHRRFLLFRRAFKQLDVEAALTKALGEVDILLTWMQKFYKL
    

Molecular Weight18162.73 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)2.11

Net Charge (pH 7.4) 1.63

Charge Density (pH 7.0) 0.0136

GRAVY Index-0.16

Hydrophobic Moment 0.68

Boman Index0.02

Instability Index42.01

Aliphatic Index 93.68

Aromaticity 0.1226

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22585.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7339.50

LogP -60.33

H-bond Donors 254.0

H-bond Acceptors 241.0

Rotatable Bonds 610.0

Heavy Atoms 1283.0

Ring Count 29.0

Amide Bonds 174.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0179368 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPredicted N-linked glycosylation of asparagine residues at positions 34, 48 and 75

Bio-Activity Profile

Function

Receptor agonist Immunomodulatory Signaling peptide

TargetInterleukin-20 receptor (Human); Interleukin-22α1/20β heteromer (Human)