Peptide Database

Peptide NameNeutrophil defensin 8 (RMAD-8)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC469H753N131O135S8

DescriptionStandard

        MRTLVILAAILLVALQAQAEPLQARTDEATAAQEQIPTDNPEVVVSLAWDESLAPKDSVPGLRKNMACYCRIPACLAGERRYGTCFYLRRVWAFCC
    

Molecular Weight10643.31 Da

Isoelectric Point (pI)6.18

Net Charge (pH 7.0)-0.54

Net Charge (pH 7.4) -0.87

Charge Density (pH 7.0) -0.0057

GRAVY Index0.16

Hydrophobic Moment 0.53

Boman Index0.06

Instability Index63.76

Aliphatic Index 97.71

Aromaticity 0.0729

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4251.06

LogP -37.76

H-bond Donors 153.0

H-bond Acceptors 143.0

Rotatable Bonds 341.0

Heavy Atoms 743.0

Ring Count 15.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0033376 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9544

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic