Peptide Database

Peptide NameDefensin-5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length110 amino acids

Chemical FormulaC527H847N161O173S7

DescriptionStandard

        MRTLTLLAALLLLALQAQAQTLQETADQVPAQDQPEAKDQGELWSEDEDEAEDGDQDVAISFTGEERLARAAGFEIKSNCKCRRRRFCKFRERHNGSCDILGHSYRLCCK
    

Molecular Weight12430.79 Da

Isoelectric Point (pI)5.02

Net Charge (pH 7.0)-5.35

Net Charge (pH 7.4) -5.79

Charge Density (pH 7.0) -0.0486

GRAVY Index-0.65

Hydrophobic Moment 0.60

Boman Index-0.19

Instability Index59.56

Aliphatic Index 73.82

Aromaticity 0.0545

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5482.41

LogP -61.67

H-bond Donors 195.0

H-bond Acceptors 177.0

Rotatable Bonds 428.0

Heavy Atoms 868.0

Ring Count 11.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0301923 VERIFIED: NO

Provenance & Taxonomy

OrganismMyotis davidii [Animal]

FamilyDefensin

Tax ID225400

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal