Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length194 amino acids

Chemical FormulaC976H1544N272O260S8

DescriptionStandard

        PKTLPMAHEPMLLLAVTELVANSAAFTYFTAGALRRNFSSDMLPRQFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPNPGHTRRAPPFPTSGLPLPQVKRLETLLKFGLWLFGVPRANSKCCPHPVP
    

Molecular Weight21504.89 Da

Isoelectric Point (pI)10.21

Net Charge (pH 7.0)9.47

Net Charge (pH 7.4) 9.04

Charge Density (pH 7.0) 0.0488

GRAVY Index-0.10

Hydrophobic Moment 0.55

Boman Index0.06

Instability Index54.10

Aliphatic Index 88.51

Aromaticity 0.0773

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8335.79

LogP -102.93

H-bond Donors 285.0

H-bond Acceptors 283.0

Rotatable Bonds 672.0

Heavy Atoms 1516.0

Ring Count 47.0

Amide Bonds 209.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0166873 VERIFIED: NO

Provenance & Taxonomy

OrganismSylvia atricapilla [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria