Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length244 amino acids

Chemical FormulaC1248H1892N282O363S9

DescriptionStandard

        IDDFTEVDYSLNSLPAVFQPFIDLNLKGTVYPAGNYTGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITIAEEVKSGKLICFLMFFFLQTCSYFNISSEIFGSIIPEVAKYSVTPYPVMLKLRATEIPIISLEQDSFTAEIQGSMEVFAVLPDSATQSLFTMNIAANTSIALNIFDQKLMGSLCLNRLQLSLAHSNVGFFEVSLLENILSYVLQAEVIPSANAKLSKGFPLP
    

Molecular Weight26942.63 Da

Isoelectric Point (pI)4.30

Net Charge (pH 7.0)-12.16

Net Charge (pH 7.4) -12.51

Charge Density (pH 7.0) -0.0498

GRAVY Index0.38

Hydrophobic Moment 0.55

Boman Index0.27

Instability Index44.96

Aliphatic Index 98.77

Aromaticity 0.1393

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0399111 VERIFIED: NO

Provenance & Taxonomy

OrganismTauraco erythrolophus [other]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria