Peptide Database

Peptide NameF21

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC107H166N28O22

DescriptionStandard

        KKAFAAAAAFAAWAAFAKKKK
    

Molecular Weight2196.64 Da

Isoelectric Point (pI)10.70

Net Charge (pH 7.0)5.75

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.2740

GRAVY Index0.19

Hydrophobic Moment 0.32

Boman Index0.10

Instability Index2.37

Aliphatic Index 52.38

Aromaticity 0.1905

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 817.23

LogP -4.46

H-bond Donors 29.0

H-bond Acceptors 28.0

Rotatable Bonds 73.0

Heavy Atoms 157.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0401794 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyRanacyclin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli DC2

Activity4 μM

MethodMIC

FIRST PREV 1 2 3 4

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