Peptide Database

Peptide NameEsculentin-1A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC212H371N59O60S3

DescriptionStandard

        GIFSKLAGKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC
    

Molecular Weight4802.77 Da

Isoelectric Point (pI)9.63

Net Charge (pH 7.0)4.74

Net Charge (pH 7.4) 4.49

Charge Density (pH 7.0) 0.1030

GRAVY Index0.22

Hydrophobic Moment 0.59

Boman Index0.10

Instability Index-8.14

Aliphatic Index 114.35

Aromaticity 0.0217

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1938.95

LogP -17.66

H-bond Donors 69.0

H-bond Acceptors 68.0

Rotatable Bonds 175.0

Heavy Atoms 334.0

Ring Count 1.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0426930 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax esculentus [Animal]

FamilyEsculentin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antibiotic

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