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MYP_165615
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Basic Information
Cupiennin-1a [F2,6K]
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
35 amino acids
C170H295N49O44S
Standard
Sequence
GKGALKKFLAKKVAKTVAKQAAKQGAKYVVNKQME
Physicochemical Analysis
3761.53 Da
10.43
8.76
8.53
0.2502
-0.51
0.69
-0.14
22.19
75.43
0.0571
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1563.04
-14.22
53.0
54.0
139.0
264.0
2.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0153812 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cupiennin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
>40 μM
HC50
PMID23523532 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23523532/
RECORD: Rec_0164223 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cupiennin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Paracoccus denitrificans
10-20 μM
MIC
PMID23523532 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23523532/
RECORD: Rec_0193576 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cupiennin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
40 μM
MIC
PMID23523532 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23523532/
RECORD: Rec_0210956 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Hemolytic Cytotoxic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0340818 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cupiennin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Drosophila melanogaster
221.3
LD50
PMID23523532 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23523532/
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