Peptide Database

Peptide NameDefensin 5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC360H571N103O108S9

DescriptionStandard

        MEKKTVAALSFLFIALFVAQEIAVTEAKTCENLSDSFKGPCIPDGNCNKHCKEKEHVLSGRCRDDFRCWCTRNC
    

Molecular Weight8358.60 Da

Isoelectric Point (pI)7.53

Net Charge (pH 7.0)0.61

Net Charge (pH 7.4) 0.15

Charge Density (pH 7.0) 0.0082

GRAVY Index-0.26

Hydrophobic Moment 0.57

Boman Index-0.07

Instability Index22.03

Aliphatic Index 65.95

Aromaticity 0.0811

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3423.22

LogP -35.83

H-bond Donors 126.0

H-bond Acceptors 120.0

Rotatable Bonds 281.0

Heavy Atoms 580.0

Ring Count 11.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0285718 VERIFIED: NO

Provenance & Taxonomy

OrganismLens ervoides [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal