Peptide Database

Peptide NameCecropin A1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC95H163N31O24

DescriptionStandard

        RVFNAAQKGLPVAAGIKGLGR
    

Molecular Weight2123.50 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1790

GRAVY Index0.17

Hydrophobic Moment 0.66

Boman Index0.08

Instability Index11.70

Aliphatic Index 102.38

Aromaticity 0.0476

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 898.55

LogP -9.18

H-bond Donors 31.0

H-bond Acceptors 28.0

Rotatable Bonds 71.0

Heavy Atoms 150.0

Ring Count 2.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0091739 VERIFIED: YES

Provenance & Taxonomy

OrganismAedes aegypti [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)