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MYP_165518
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
5 amino acids
C21H40N6O8
Standard
Sequence
GLTSK
Physicochemical Analysis
504.58 Da
8.75
0.76
0.55
0.1518
-0.40
0.19
-0.04
8.00
78.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
246.20
-3.48
9.0
9.0
17.0
35.0
0.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0104014 VERIFIED: YES
Provenance & Taxonomy
Phaseolus vulgaris [Plant]
Bioactive peptides
3885
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic Immunomodulatory
PaperPubMed PMID 29287362 PMID29287362 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29287362/
RECORD: Rec_0106890 VERIFIED: YES
Provenance & Taxonomy
Phaseolus vulgaris [Plant]
3885.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperLuna-Vital D. A., Gonzalez de Mejia E., Mendoza S., Loarca-Pina G.. Peptides present in the non-digestible fraction of common beans (Phaseolus vulgaris L.) inhibit the angiotensin-I converting enzyme by interacting with its catalytic cavity independent of their antioxidant capacity. Food Funct., 6, 1470-1479, 2015.
RECORD: Rec_0254519 VERIFIED: YES
Provenance & Taxonomy
Phaseolus vulgaris [Plant]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
65.4±0.38 μM
IC50
RECORD: Rec_0273888 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0381992 VERIFIED: YES
Provenance & Taxonomy
Phaseolus vulgaris [Plant]
3885.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
65.4
IC50
PaperLuna-Vital D. A., Gonzalez de Mejia E., Mendoza S., Loarca-Pina G.. Peptides present in the non-digestible fraction of common beans (Phaseolus vulgaris L.) inhibit the angiotensin-I converting enzyme by interacting with its catalytic cavity independent of their antioxidant capacity. Food Funct., 6, 1470-1479, 2015.