Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length221 amino acids

Chemical FormulaC1105H1693N253O340S8

DescriptionStandard

        QIDDLAEVDYSLNSLPAVFPPFIDLDLKGAVVPAGNYTGSPYVAASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTLAEETCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVINLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTLNIAANTSISLNIFDQKLMGSLCLNRLQFSLAHSNVGSFEVLLLENILSYILQTEVIPSANGK
    

Molecular Weight24218.27 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-17.14

Net Charge (pH 7.4) -17.48

Charge Density (pH 7.0) -0.0776

GRAVY Index0.33

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index44.94

Aliphatic Index 101.95

Aromaticity 0.1176

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0009066 VERIFIED: NO

Provenance & Taxonomy

OrganismPicathartes gymnocephalus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria