Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC983H1551N269O261S8

DescriptionStandard

        PLTPPVAHEPMLLLAVTEFVANSAAFTYFTAGALRRTISSDMLPRRFPLQLRTKSMEVFSPQLQEHYPDQPMELHLWARRQPLLSCHPDALHGALFSSAEAFVVLPNATRAPAFVLNIDANVTAKPTITRNRLGGTMRLTGLVPGPELAWTPLPALCQAQGLPVPQVKRLETLLKFGLWLFGVPRANSKCSPHPVP
    

Molecular Weight21570.00 Da

Isoelectric Point (pI)9.73

Net Charge (pH 7.0)6.47

Net Charge (pH 7.4) 6.04

Charge Density (pH 7.0) 0.0330

GRAVY Index0.04

Hydrophobic Moment 0.57

Boman Index0.11

Instability Index59.14

Aliphatic Index 93.62

Aromaticity 0.0765

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8252.75

LogP -99.69

H-bond Donors 282.0

H-bond Acceptors 281.0

Rotatable Bonds 669.0

Heavy Atoms 1521.0

Ring Count 48.0

Amide Bonds 209.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010408 VERIFIED: NO

Provenance & Taxonomy

OrganismPhainopepla nitens [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria