Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length149 amino acids

Chemical FormulaC728H1162N204O218S7

DescriptionStandard

        MKQQASLSLGRWSLWLLLLGLALPSASAQALSYREAVLRAVDRINDGSTEAHLYRLLELDPPPKDLPGTRKAVSFRVKETVCPRPSLQPPEQCDFKENGLTLGLVKQCLGTVSLDRSDDQFDINCNEASGPFCVGHMLTGWVEKHPLDQ
    

Molecular Weight16484.71 Da

Isoelectric Point (pI)5.89

Net Charge (pH 7.0)-2.26

Net Charge (pH 7.4) -2.74

Charge Density (pH 7.0) -0.0152

GRAVY Index-0.27

Hydrophobic Moment 0.79

Boman Index-0.01

Instability Index35.77

Aliphatic Index 92.28

Aromaticity 0.0604

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6739.16

LogP -66.82

H-bond Donors 234.0

H-bond Acceptors 226.0

Rotatable Bonds 540.0

Heavy Atoms 1157.0

Ring Count 26.0

Amide Bonds 160.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111929 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus x Bos taurus [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal