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MYP_165408
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Basic Information
Lactoglobulin beta [007-009]
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C13H26N4O4S
Standard
Sequence
MKG
Physicochemical Analysis
334.43 Da
8.50
0.50
0.28
0.1665
-0.80
0.57
-0.13
-21.63
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
147.54
-1.12
5.0
6.0
12.0
22.0
0.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0328337 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
71.85
IC50
PaperHern¨¢ndez-Ledesma B., Ramos M., Recio I., Amigo L.. Effect of beta-lactoglobulin hydrolysis with thermolysin under denaturing temperatures on the release of bioactive peptides. J. Chromatogr. A, 1116, 31-37, 2006.
RECORD: Rec_0344828 VERIFIED: NO
Provenance & Taxonomy
Salvia hispanica [Plant]
ACE-inhibitory peptide
4116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
71.8 μM
IC50
PaperWhey Proteins as Source of Bioactive Peptides Against Hypertension
RECORD: Rec_0365731 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
24 μM
IC50
PaperStructural Requirements of Angiotensin I-Converting Enzyme Inhibitory Peptides: Quantitative Structure-Activity Relationship Modeling of Peptides Containing 4-10 Amino Acid Residues
RECORD: Rec_0418877 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Lactoglobulin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
71.8 μM
IC50
PaperEffect of β-lactoglobulin hydrolysis with thermolysin under denaturing temperatures on the release of bioactive peptides | Hernandez-Ledesma, B. et al. | DOI: 10.1016/j.chroma.2006.03.006 Evidence URLhttps://www.uniprot.org/uniprotkb/P02754/entry
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