Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC102H158N30O34S5

DescriptionStandard

        GIVEQCCHRKCSIYDMENYCN
    

Molecular Weight2508.85 Da

Isoelectric Point (pI)5.44

Net Charge (pH 7.0)-1.19

Net Charge (pH 7.4) -1.51

Charge Density (pH 7.0) -0.0566

GRAVY Index-0.54

Hydrophobic Moment 0.28

Boman Index-0.13

Instability Index33.82

Aliphatic Index 50.95

Aromaticity 0.0952

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1063.78

LogP -11.59

H-bond Donors 40.0

H-bond Acceptors 39.0

Rotatable Bonds 83.0

Heavy Atoms 171.0

Ring Count 3.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143469 VERIFIED: YES

Provenance & Taxonomy

OrganismPetromyzon marinus [Animal]

FamilyInsulin

Tax ID7757

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0289611 VERIFIED: YES