Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC165H256N46O48S6

DescriptionStandard

        DHYICVKKGGTCNFSPCPLFNRIEGTCYSGKAKCC
    

Molecular Weight3844.47 Da

Isoelectric Point (pI)8.64

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.43

Charge Density (pH 7.0) 0.0796

GRAVY Index-0.24

Hydrophobic Moment 0.40

Boman Index-0.01

Instability Index37.28

Aliphatic Index 44.57

Aromaticity 0.1143

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1511.96

LogP -17.22

H-bond Donors 58.0

H-bond Acceptors 58.0

Rotatable Bonds 123.0

Heavy Atoms 265.0

Ring Count 7.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0054606 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyseter macrocephalus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)