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MYP_165346
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Basic Information
Ranatuerin-2CHb
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
28 amino acids
C125H224N34O37S3
Standard
Sequence
GLMDTIKGVAKNVAASLLEKLKCKVTGC
Physicochemical Analysis
2891.52 Da
9.24
2.74
2.50
0.0978
0.40
0.59
0.11
-16.95
111.43
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1157.50
-11.13
42.0
43.0
103.0
199.0
0.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073811 VERIFIED: YES
Provenance & Taxonomy
Lithobates chiricahuensis [Animal]
Ranatuerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
23-28
Bio-Activity Profile
Antimicrobial Antifungal
PaperJ.M. Conlon et al. / Peptides 32 (2011) 664-669. Characterization of antimicrobial peptides in skin secretions from discrete populations of Lithobates chiricahuensis (Ranidae) from central and southern Arizona
RECORD: Rec_0125565 VERIFIED: YES
Provenance & Taxonomy
Lithobates chiricahuensis [Animal]
Ranatuerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
23-28
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
120.0 μM
HC50
PaperJ.M. Conlon et al. / Peptides 32 (2011) 664-669. Characterization of antimicrobial peptides in skin secretions from discrete populations of Lithobates chiricahuensis (Ranidae) from central and southern Arizona
RECORD: Rec_0127694 VERIFIED: YES
Provenance & Taxonomy
Lithobates chiricahuensis [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-28
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli ATCC 25726
20 μM
MIC
PaperCharacterization of antimicrobial peptides in skin secretions from discrete populations of Lithobates chiricahuensis (Ranidae) from central and southern Arizona
RECORD: Rec_0165584 VERIFIED: YES
Provenance & Taxonomy
Lithobates chiricahuensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus
80 μM
MIC
RECORD: Rec_0258676 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
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