Peptide Database

Peptide NameLantibiotic michiganin-A (Bacteriocin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC92H153N25O30S4

DescriptionStandard

        SSSGWLCTLTIECGTIICACR
    

Molecular Weight2217.61 Da

Isoelectric Point (pI)5.71

Net Charge (pH 7.0)-0.58

Net Charge (pH 7.4) -0.84

Charge Density (pH 7.0) -0.0275

GRAVY Index0.89

Hydrophobic Moment 0.16

Boman Index0.28

Instability Index113.87

Aliphatic Index 97.62

Aromaticity 0.0476

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 881.69

LogP -10.70

H-bond Donors 37.0

H-bond Acceptors 34.0

Rotatable Bonds 70.0

Heavy Atoms 151.0

Ring Count 2.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0325742 VERIFIED: YES

Provenance & Taxonomy

OrganismClavibacter michiganensis subsp [Bacterium]

FamilyBacteriocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other ModsA post-tranlational structure was proposed based on similaity to actagardine: A lanthionine ring between S2 and C7 and two methyllanthionine rings (T10-C18 and T15-C20). T8 is dehydrated into Dhb. This led to C13 free

Bio-Activity Profile

Function

Antimicrobial

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