Peptide Database

Peptide NameArenicin-3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC115H170N36O27S4

DescriptionStandard

        GFCWYVCVYRNGVRVCYRRCN
    

Molecular Weight2617.06 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)3.72

Net Charge (pH 7.4) 3.45

Charge Density (pH 7.0) 0.1770

GRAVY Index-0.05

Hydrophobic Moment 0.77

Boman Index-0.12

Instability Index23.51

Aliphatic Index 55.24

Aromaticity 0.2381

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1055.58

LogP -8.68

H-bond Donors 44.0

H-bond Acceptors 35.0

Rotatable Bonds 79.0

Heavy Atoms 182.0

Ring Count 6.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0059550 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetKlebsiella aerogenes ATCC 13048

Activity1 μg/mL

MethodMIC

RECORD: Rec_0215229 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0251697 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEnterobacter cloacae ATCC 13047

Activity1 μg/mL

MethodMIC

RECORD: Rec_0260462 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetHuman embryonic kidney HEK293 cells (50% Cell death at 271 microg/ml, Human kidney proximal tubule HK-2 cells (50% Cell death at 170 microg/ml, Human erythrocytes (10% Hemolysis at 204 microg/ml

Activity293 μg/mL

MethodHemolysis

RECORD: Rec_0360285 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 25404

Activity0.5 μg/mL

MethodMIC