Peptide Database

Peptide NameDefensin beta 1 (beta-defensin 1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC339H528N88O84S9

DescriptionStandard

        MKVLYLLLLPLCFLFSQIAPGAGIMAVFHRYPEYVCAKKGGTCNFSPCPRFTRIEGSCYQGRAKCCV
    

Molecular Weight7468.94 Da

Isoelectric Point (pI)9.14

Net Charge (pH 7.0)5.52

Net Charge (pH 7.4) 5.13

Charge Density (pH 7.0) 0.0823

GRAVY Index0.41

Hydrophobic Moment 0.50

Boman Index0.17

Instability Index34.37

Aliphatic Index 82.99

Aromaticity 0.1343

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2706.27

LogP -19.67

H-bond Donors 101.0

H-bond Acceptors 100.0

Rotatable Bonds 236.0

Heavy Atoms 520.0

Ring Count 15.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013503 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllostomus discolor [Animal]

FamilyDefensin

Tax ID89673

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal